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SULFOBROMOPHTHALEIN SODIUM |
| Synonyms. Sulfobromophthalein sodium; BSP; Bromsulfalein sodium disodium salt hydrate; Disodium 6,6'-dihydroxy-3,3'-(4,5,6,7-tetrabromo-1,3-dihydro-3-oxoisobenzofuran- 1-ylidene)dibenzene sulphonate; Sodium sulfobromophthalein; 4,5,6,7-Tetrabromo-3',3''-disulfophenolphthalein disodium salt; 5,5'-(4,5,6,7-Tetrabromo-3-oxo-1(3H)-isobenzofuranylidene)bis(2-hydroxybenzenesulfonic acid) disodium salt; Brom-tetragnost; Bromosulfalein; Bromosulfophthalein; Bromosulphthalein; Bromotaleina; Bromsulfalein; Bromsulfan; Bromsulfophthalein; Bromsulfthalein; Bromsulphalein; Bromsulphalein R sodium; Bromthalein; BSF; BSP sodium; Disodium bromosulfophthalein; Disodium phenoltetrabromophthalein sulfonate; Hepartestabrome; Hepatestabrome; Hepatosulfalein; Sodium bromosulfalein; Sodium bromosulfophthalein; Sodium bromsulphalein; Sodium bromsulphthalein; Sodium phenol tetrabromophthalein; Sodium sulphobromophthalein; Sulphobromophthalein sodium; Tetrabromophenolsulfophthalein; |
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| PRODUCT IDENTIFICATION | |
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CAS RN |
71-67-0 (Anhydrous), 123359-42-2 (Hydrate) |
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EINECS RN |
200-761-0 |
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FORMULA |
C20H8Br4Na2O10S2 |
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MOLE WEIGHT |
838.03 |
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H.S CODE |
2932.20.2000 |
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SMILES |
C1(c2c(c(c(Br)c(c2Br)Br)Br)C(O1)=O)(c1cc(c(O)cc1)S(=O)(=O)[O-])c1cc (c(O) cc1) S(=O)(=O)[O-].[Na+].[Na+] |
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CLASSIFICATION |
Coloring agent, Indicator, Phenolphthalein |
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EXTRA NOTES |
Biochem/physiol Actions:Sulfobromophthalein (BSP) is a high affinity substrate for organic anion transporting polypeptides (OATPs) and has been used as a substrate for multidrug resistance associated protein (Mrp2). BSP is transported into hepatocytes by OATPs and, after conjugation to glutathione, is excreted into bile by Mrp2. It was found to inhibit the aldo-keto reductase ARK1C20 [sigmaaldrich] |
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| PHYSICAL AND CHEMICAL PROPERTIES | |
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PHYSICAL STATE. |
white powder |
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MELTING POINT |
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BOILING POINT |
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DENSITY |
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SOLUBILITY IN WATER |
Soluble |
| SOLVENT SOLUBILITY |
Slightly soluble in ethanol and acetone |
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VAPOR DENSITY |
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log P(octanol-water) |
-0.07 |
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VAPOR PRESSURE |
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AUTOIGNITION TEMP |
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| pK |
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REFRACTIVE INDEX |
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FLASH POINT |
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| STABILITY AND REACTIVITY | |
| STABILITY | Stable under normal conditions. |
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INCOMPATIBLE MATERIALS |
Strong oxidizing agents |
| POLYMERIZATION |
Has not been reported |
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NFPA RATINGS |
Health: 2, Flammability: 0, Reactivity: 0 |
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| EXTERNAL LINKS & GENERAL DESCRIPTION |
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USA.gov - Sulfobromophthalein Wikipedia Linking - Sulfobromophthalein Google Scholar Search - Sulfobromophthalein U.S. National Library of Medicine - Sulfobromophthalein sodium PubChem Compound Summary - Sulfobromophthalein KEGG (Kyoto Encyclopedia of Genes and Genomes) - Sulfobromophthalein http://www.ebi.ac.uk/chebi/ - Sulfobromophthalein sodium http://www.ncbi.nlm.nih.gov/ - Sulfobromophthalein Hazardous Substances Data Bank - Sulfobromophthalein EPA - Substance Registry Services - Sulfobromophthalein ATC code: V04CE02 |
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| SALES SPECIFICATION | |
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APPEARANCE |
white powder |
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IDENTIFICATION |
Conforms to structure (IR) |
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LOSS ON DRYING |
7% max |
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HEAVY METALS |
10ppm max |
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| TRANSPORT & REGULATORY INFORMATION | |
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UN NO. |
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| HAZARD CLASS |
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| PACKING GROUP | |
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| SAFETY INFORMATION | |
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HAZARD OVERVIEW |
GHS (Globally Harmonised System) Classification: Respiratory sensitisation. Skin sensitisation. Hazard statements: May cause an allergic skin reaction. May cause allergy or asthma symptoms or breathing difficulties if inhaled. |
| SIGNAL WORD | Warning |
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PICTOGRAMS |
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HAZARD STATEMENTS |
H317-H334 |
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P STATEMENTS |
P261-P280-P342 + P311 |
| EC DIRECTIVES |
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| HAZARD CODES |
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RISK PHRASES |
42/43 |
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SAFETY PHRASES |
22-36/37-45 |
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| PACKING |
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Preserved in light-resistant and well-closed bottles |
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